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Staff Detail

Asst. Prof. Dr. ILGIN ÇAĞNAN ÇAKKOL

Asst. Prof. Dr. ILGIN ÇAĞNAN ÇAKKOL

Duty: Faculty Member
Department: Biological Sciences
Office: AS112
Tel: +90 392 630 2675
E-Mail: ilgin.cagnan@emu.edu.tr

Download "CV (PDF)"

Education

Education

2018

PHD

UNIVERSITY, KÖK HÜCRE,

2009

MS

UNIVERSITY, YAŞAM BİLİMLERİ,

2008

BS

UNIVERSITY, BİYOLOJİK BİLİMLER,

Publications

Publications

SCI- Expanded

Conferences

Conferences

  • PKNOX2 proteomics reveals novel interactions with ATM and RPS3A in bone marrow-derived mesenchymal stem cells
  • TGF-ß1 Production By Bone Marrow Mesenchymal Stem Cells of FANCD2 Differs from Other Fanconi Anemia Complementation Groups
  • PKNOX2 regulated by TGFbeta is a new candidate to explain bone marrow failure in fanconi anemia
  • PKNOX2 level of mesenchymal stem cells prompts hematopoietic stem cell differentiation towards myeloid lineages in coculture experiments.
  • Mesenchymal stem cells induce proliferation of NCI-H82 small cell lung cancer
  • PCR3::GITRL transfected MSCs induce apoptotic cell death and SIVA1 expression in SCLC-21H lung cancer cell line
  • Genome-wide non-coding RNA expression profile indicates upregulation of hsa-miR-761 in the bone marrow mesenchymal stromal cells of Fanconi Anemia patients
  • miRNA expression profiling in mesenchymal stromal/stem cells derived from G-CSF primed bone marrows
  • Gene expression of Notch receptors and ligands by plastic adherent and prospectively isolated MSCs
  • HOX and TALE gene expression profile of bone marrow derived mesenchymal stem/stromal cells from Fanconi anaemia patients and donors.
  • HOXA1, HOXA7 and HOXB7 gene expression are deregulated in mesenchymal stromal/stem cells derived from G-CSF primed bone marrows
  • Fankoni anemili hastaların kemik iliği mezenkimal kök hücrelerinde PREP2 gen ifadesi donörlere oranla düşüş göstermektedir
  • PREP1 overeksprese eden kemik iliği kaynaklı mezenkimal kök hücrelerinde TALE homeodomain protein düzeyleri
  • Fankoni anemili hastalardan elde edilen mezenkimal kök hücrelerin proliferasyon ve yaşlanma özellikleri
  • Sağlıklı insan kemik iliği endosteal ve santral bölgelerinde sitokin ekspresyonları ve G-CSF etkisi
  • HOX-TALE expression patterns in Fanconi anaemia
  • Expression of hsa-miR-3065-3p was significantly downregulated in Fanconi anaemia patient bone marrow derived mesenchymal stem cells following bone marrow transplantation.
  • Random forest and support vector machines analyses of HOX-TALE gene expressions of Fanconi anaemia patient’s bone marrow mesenchymal stem cells
  • Effects of in-vivo G-CSF stimulation on cytokine levels in bone marrow plasma samples from healthy donors
  • Assessment of human bone marrow plasma samples suggests a different role for mesenchymal stromal cells in distinct areas mediated by PDGF-BB/PDGF-R
  • Differential cytokine expression profile of healthy human bone marrow plasma samples from the endosteal and vascular region
  • Differential miRNA expression profile of bone marrow derived mesenchymal stem cells in fanconi anemia patients and healthy donors
  • Human bone marrow derived mesenchymal stem cells show heterogeneous mRNA levels of glucocorticoid induced tumor necrosis factor receptor (GITR) and its ligand (GITRL)
  • Hox-TALE genes show highly conserved yet heterogeneous expression profiles among Fanconi anaemia patients and healthy donors
  • Expression of Hox genes in the bone marrow derived mesenchymal stromal/stem cells from Fanconi anaemia patients changes following bone marrow transplantation
  • Whole-exome sequencing in combination with simultaneous analysis of homozygous stretches of exome variants identified causative mutations in two genes in Malpuech syndrome
  • Homozygosity mapping and mutation analysis of the HPSE2 gene support genetic homogeneity in Urofacial Syndrome
Projects

Projects

  • Cyprus Dysmenorrhea (CypDy) Project ,[EuropeAid/173620/DH/ACT/CY programme awarded to KISAD (Number of proposal: TCC/2022/173620-1/5) ,EuropeAid/173620/DH/ACT/CY programme awarded to KISAD (Number of proposal: TCC/2022/173620-1/5) (06.01.2023) ]
  • Period Poverty ,[Avrupa Birliği tarafından finanse edilen Sivil Büyü programı ,11044 (07.04.2022-03.10.2023) ]
  • HOX and TALE Transcription Factors in Fanconi Anemia Bone-Marrow Mesenchymal Stem Cells: Gene Expression and Protein Interactions ,[TUBITAK ,214Z033 (01.05.2015-01.02.2018) ]
  • Expression, Control and Diagnostic Role of the Cholinergic Receptor Nicotinic Alpha 5 (CHRNA5) Gene in Breast Cancer ,[TUBITAK ,111T316 (01.12.2011-01.12.2014) ]
  • Effect of Glucocorticoid-Induced TNFR Protein Ligand (GITRL) Transfected Mesenchymal Stem Cells (MSCs) on Lung Cancer ,[TÜBİTAK ,112T474 (15.10.2012-15.10.2014) ]
  • HOX/TALE Gene Expression Profiling of the Bone Marrow Derived Mesenchymal Stem Cells from Fanconi anemia Patients and Searching the Correlation Between the whole Genome miRNA Expression Microarray ,[TÜBİTAK ,110S021 (01.10.2010-01.04.2014) ]
Awards

Awards

  • Short Term Scientific Missions (2013)
  • COST Training School (2011)
  • Publication Award by EMU (2023)
  • Publication Award by EMU (2022)
  • Publication Award by EMU (2021)
  • Publication Award by EMU (2021)
  • Publication Award by EMU (2021)
  • Meliha Terzioğlu Bilim Ödülü (2018)
  • 2nd Prize for Poster Presentation (2014)
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